Factor XIII Deficiency

Factor XIII  is an inherited bleeding disorder that is caused by complications with factor XIII when the clotting reaction is blocked too soon causing the blood clot to not form. The deficiency of the clotting factor is either the body does not make enough factor XIII or factor XIII is not working like it should.

According to hemophilia.org, FactorXIII protein stabilizes the formation of a blood clot. Without it, a clot will still develop, but will then break down and cause recurrent bleeds. Umbilical cord bleeding is common in factor XIII deficiency, reported in almost 80% of cases. Up to 30% of patients sustain a spontaneous intracranial hemorrhage, a brain bleed, which is the leading cause of mortality. Other symptoms of factor XIII deficiency include bruising, nose and mouth bleeds, muscle bleeds and delayed bleeding after surgery.

Women can experience menorrhagia, long, heavy menstrual periods, and repeat miscarriages. Men with FXIII deficiency may show signs of infertility.

Factor XIII Deficiency Treatment

Corifact is approved for patients with congenital FXIII deficiency, a rare inherited condition affecting both men and women. Corifact is indicated for routine prophylactic treatment and perioperative management of surgical bleeding in adult and pediatric patients with congenital Factor XIII (FXIII) deficiency.

HF Healthcare provides Corifact used to treat factor XIII deficiency and we can create a manageable care plan that works in concert with your physician and insurance payer. We are here to guide you to a healthy future!